I just wanted to say my answers are pretty much the same as everyone elses except for me accessing it doesn't hurt at all. Its a quick prick, less than getting blood drawn and then I usually forget its there. When ever I'm on IVs I get all my weekly blood work drawn from my port. The only thing I have trouble with is they usually don't get blood return when its first accessed, but after a couple doses of meds it gets perfect blood return. I've been told this isn't real common but I've never had any problems with clotting or anything. I would also say ask your surgeon about your options as far as location goes. Part of the reason I waited so long to get one was because I didn't want it up in my chest where it would be real noticable. My surgeon was awesome and was able to put it lower in my rib area kinda on the side. The only time anyone can see it is when I have a bathing suit on. Its honestly the best thing I've ever done, I wish I would have done it a long time ago! Good luck with yours!