Fortunately I've been blessed with a hell of a tolerance for alcohol. I can drink most of my friends under the table & NEVER wake up with a hangover... sure I've woken up a few times still drunk from the night before, but never really sick from drinking. I really think you should check with your CF doctor to see if taking Advil, or anything with Ibuprofen is okay for you. I know that I've been told and have experienced Hemoptisis (throwing up blood) several times from over usage of Advil. The Ibuprofen does reduce inflamation, but can cause Hemoptisis. I am actually replying to this in the hospital. I've been in on IV antibiotics for 2 weeks (cephtaz & tobra) and should be out in time for Christmas. About a month ago I became really congested and tight, so I started taking Advil to releave the feeling. After 4 days of work I found myself sitting at my desk in work throwing up a lot of blood. That told me to stop the Advil & have the doctors get rid of the congestion. I assume that you are probably using Pulmozyme, as it greatly helps our situation. If your using Advil and it causes you to continuously throw up blood, the doctors will stop you from using the Pulmozyme, as it may cause additonal blood loss. It's not good to have to stop the Pulmozyme, as it has done wonders for prolonging lung damage. If you ever want to talk or have any questions, feel free to e-mail me (farbeyond1978@yahoo.com) I would be glad to B.S with anyone. Take it easy & good luck!!!Drink recommendation: Grateful Dead